Vitamins are essential compounds for many functions in humans. Research shows that in addition to their specific functions, certain vitamins are useful for prevention and topical treatment of photoaging and chronological skin aging.
The skin is constantly exposed to solar radiation and pollution, which induce the formation of ‘free radicals’ and ‘reactive oxygen species’ (ROS); free radicals are molecules or fragments of molecules that contain one or more unpaired electrons in their external orbitals. Topically applied antioxidants are capable of preventing and reducing UV-induced skin damage, by protecting skin cells against the action of ROS.
However, antioxidants are notoriously unstable and may become easily oxidized and inactive. For effective topical use, an antioxidant must be stable after it is included in the final product and applied to the skin. Generally, antioxidants are more stable in acidic pH. Previous research has also indicated that adding ferulic acid increases the stability of a solution of l-ascorbic (vitamin C).
Vitamin C is the most abundant antioxidant in the human skin. Vitamin C is water soluble, and functions in the aqueous compartment of the cell as a ‘free radical scavenger.’ By donating electrons, it neutralizes free radicals and protects intracellular structures from oxidative stress. Topically applied vitamin C has many benefits; it is anti-inflammatory, promotes collagen synthesis and lightens hyperpigmentation.
Issa, M. C. A., & Tamura, B. (Eds.). (2017). Daily Routine in Cosmetic Dermatology. Springer International Publishing
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